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undifferentiated tissue formed by the cambium. carbon. hydrogen. and oxygen in a proportion of usually as the result of wounding (contrast with woundwood).

callus (Wikipedia)

A callus (pl.: calluses) is an area of thickened and sometimes hardened skin that forms as a response to repeated friction, pressure, or other irritation. Since repeated contact is required, calluses are most often found on the feet and hands, but they may occur anywhere on the skin. Some degree of callus, such as on the bottom of the foot, is normal.

Callus
Examples of callus found on the toe
SpecialtyDermatology
ComplicationsSkin ulceration, infection
Calluses (plantar in right foot and medial in left foot)

Calluses are generally not harmful and help prevent blisters, as well as offering protection. However, excessive formation may sometimes lead to other problems, such as a skin ulceration or infection, or cause the affected person to try to offload the affected painful area, which can place excessive stress on the asymptomatic side.

Rubbing that is too frequent or forceful will cause blisters, as opposed to calluses, to form.

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